1、作为课题负责人或技术骨干能独立开展创新药物的研究开发的工作;
2、根据课题需要,查阅文献合理设计合成路线独立按时完成有机小分子药物分子和中间体的合成和表征;
3、分析整理活性数据和构效关系,提出合理的假设,运用包括计算机辅助设计等手段发现和优化先导化合物;
4、定期整理汇报研究结果,推动课题进展;
5、指导下属的研究工作;
6、保持真实详细清楚整洁的实验记录和干净的实验环境;
7、关注研究领域最新进展,提升自身能力和对课题的贡献;
8、Work independently in a collaborative team environment discovering novel therapeutics;
9、Design, synthesize, purify and characterize novel organic compounds for a variety of therapeutic applications using modern synthetic and analytical techniques;
10、Develop strategies for lead generation through hit validation and expansion, lead optimization and computer-based drug design approaches;
11、Analyze biological data and establish structure-activity relationship for the research programs;
12、Supervise junior research stuff members (research associate, associate scientist, or research scientist);
13、Summarize and present research results in the project and department meetings;
14、Keep abreast of the current development in the area of research focus。
任职要求:
1、有机化学,药物化学或相关专业博士或同等理论及实验水平,5年以上相关研究或工作经历;
2、具有丰富的有机实验室和小分子药物研发能力,熟练掌握有机合成、产物分离与结构鉴定技能;
3、工作主动敬业,踏实认真,责任心强,具有很好的创新和抗压能力;
4、具有基于结构的药物设计以往经验为佳;
5、具有优秀的沟通和执行能力,良好的团队协作精神;
6、Multiple positions available depending on experiences and qualifications;
7、Ph、 D or equivalent in synthetic, organic, or medicinal chemistry with 5+ years postdoctoral experience in the relevant fields;
8、Previous experience in small molecule drug discovery in a pharmaceutical or biotechnology environment is highly desirable;
9、Highly motivated, innovative researcher capable of critical thinking and ability to work effectively as part of a team in a fast-paced environment;
10、Proven track record of high productivity and strong organic and/or medicinal chemistry bench skills;
11、Experience or working knowledge of structure-based drug design is a plus;
12、Excellent communication, organizational, and multi-tasking skills are required。
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药物化学研究员Research Scientist (Medicinal Chemistry)
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、作为课题技术骨干能独立进行创新药物的研究开发的工作;
2、根据课题需要,查阅文献合理设计合成路线独立按时完成有机小分子药物分子和中间体的合成和表征;
3、分析整理活性数据和构效关系,提出合理的假设,运用包括计算机辅助设计等手段发现和优化先导化合物;
4、定期整理汇报研究结果,推动课题进展;
5、指导助理研究员的研究工作;
6、保持真实详细清楚整洁的实验记录和干净的实验环境;
7、关注研究领域最新进展,提升自身能力和对课题的贡献;
8、Work independently in a collaborative team environment discovering novel therapeutics;
9、Design, synthesize, purify and characterize novel organic compounds for a variety of therapeutic applications using modern synthetic and analytical techniques;
10、Develop strategies for lead generation through hit validation and expansion, lead optimization and computer-based drug design approaches;
11、Analyze biological data and establish structure-activity relationship for the research programs;
12、Supervise junior research stuff members (research associate, associate scientist);
13、Summarize and present research results in the project and department meetings;
14、Keep abreast of the current development in the area of research focus。
任职要求:
1、有机化学,药物化学或相关专业博士或同等理论及实验水平,0-5年相关研究或工作经历;
2、具有丰富的有机实验室和小分子药物研发能力,熟练掌握有机合成、产物分离与结构鉴定技能;
3、工作主动敬业,踏实认真,责任心强,具有很好的创新和抗压能力;
4、具有基于结构的药物设计以往经验为佳;
5、具有优秀的沟通和执行能力,良好的团队协作精神;
6、Multiple positions available depending on experiences and qualifications;
7、Ph、 D or equivalent in synthetic, organic, or medicinal chemistry with 0 to 0- 5 years postdoctoral experience in the relevant fields;
8、Previous experience in small molecule drug discovery in a pharmaceutical or biotechnology environment is highly desirable;
9、Highly motivated, innovative researcher capable of critical thinking and ability to work effectively as part of a team in a fast-paced environment;
10、Proven track record of high productivity and strong organic and/or medicinal chemistry bench skills;
11、Experience or working knowledge of structure-based drug design is a plus;
12、Excellent communication, organizational, and multi-tasking skills are required。
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药物化学部助理研究员Research Associate(Medicinal Chemistry)
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、查阅文献,初步设计合成路线,独立按时完成有机小分子药物分子和中间体的合成和表征;
2、保持真实详细清楚整洁的实验记录和干净的实验环境;
3、积极参与项目的讨论,提出合理的建议;
4、Synthesize, purify and characterize intermediates and final compounds for testing against biological targets;
5、Analyze spectroscopic data to ensure the identity and integrity of synthesized molecules;
6、Conduct literature and database searches for reaction conditions and be aware of the current progress in the research focus;
7、Maintain accurate documentation of experiments and research results;
8、Propose target molecules and synthetic plans to supervisor and project team;
9、Present research results in project and department meetings。
任职要求:
1、有机化学或相关专业学士或硕士或同等理论及实验水平,工作经验不限;
2、具有有机实验室实际经验,熟练掌握有机合成、产物分离与结构鉴定技能;
3、工作主动敬业,踏实认真,责任心强;
4、良好的沟通能力和团队精神;
5、B.S. or M.S. degree in organic chemistry, medicinal chemistry or relevant disciplines;
6、Strong small molecule synthetic organic chemistry skills, with the ability to independently plan and execute synthetic approaches to target molecules;
7、Strong background and experience in common spectroscopy (NMR, HPLC, MS) and modern analytical techniques required;
8、Highly motivated, pleasant personality to work efficiently as part of a team in a fast-paced environment;
9、Excellent communication and organizational skills。
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计算化学研究员Research Scientist (Medicinal Chemistry)
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、希望能够组建和领导一个计算化学/计算生物学团队,将来也能开发AI,以支持新药研发;
2、负责创新药物的计算机辅助药物设计及AI药物研发平台的建设与管理;
3、利用现代计算化学技术原理,为研发项目进行分子设计,提出合理的假设,运用包括计算机辅助设计等手段发现和优化先导化合物;
4、和其他药物研发团队一起制定和推进药物研发的策;
5、领导实现“先设计再合成”(Design before Synthesis)的高效药物研发模式;
6、积极跟踪计算机辅助药物设计最新动态,及时引进新技术,新方法;
7、关注研究领域最新进展,定期整理汇报研究结果,推动课题进展。
1、作为项目负责人,负责细菌感染疾病或相关免疫系统疾病的新型治疗药物的研究开发;
2、负责药物研发过程中生物靶点识别、靶点验证、疾病机制或生物标记物研究;
3、负责实验数据的分析及解释、报告撰写等,针对项目进展与项目成员或合作者进行有效沟通;
4、项目或部门会议上汇报工作及讨论;
5、指导下属进行研究工作;
6、及时了解相关研究领域的最新进展;
7、Work independently in a collaborative team environmentdiscovering novel therapeutics for bacterial infection disease or immunologic disease;
8、Design, perform and optimize assays for target identification,validation, mechanistic study as well as biomarker study;
9、Analyze and interpret experimental data, communicate with team members and collaborators on working progress;
10、Summarize and present research results in the project and department meetings;
11、Supervise junior research stuff members (research associate, associate scientist, or research scientist);
12、Keep abreast of the current development in the area of research focus;
13、Act as the scientific resource for the related diseases。
任职要求:
1、微生物学、免疫学或相关专业,5年以上相关研究经历,博士或同等以上学历;
2、具有在工业界小分子化合物药物开发经验者优先考虑;
3、具备药物靶点识别、相关疾病机制研究或生物标记物研究经验者优先考虑;
4、对相关研究领域有深入的了解;
5、具备实验设计、操作、解释及解决问题的能力;
6、对科研工作有热情及兴趣,具有很强的创新意识和学习能力,积极主动,责任心强;
7、具有良好的团队协作精神和沟通能力;
8、根据该应聘者的实际工作经验及能力、背景等,我们可能提供资深研究员(Principal Research Scientist)、高级研究员(Senior Research Scientist)实验室负责人、研究项目负责人、等不同职位;
9、 Ph、D or equivalent in microbiology or immunology, with 5+ years relevant postdoctoral experience;
10、Industrial experience in small molecule drug development is preferred;
11、Research experience in target identification, disease mechanistic study as well as biomarker study is a desirable;
12、A broad knowledge and deep understanding of disease biology is a must;
13、Demonstrated ability to independently design, execute, interpret, and troubleshoot experiments;
14、Demonstrated ability to balance multiple priorities and timelines;
15、Must be a team player with pro-active behavior, excellent communication, organizational and multi-tasking skills;
16、Highly motivated, innovative researcher capable of critical thinking and ability to work effectively as part of a team in a fast-paced environment。
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生物学(Biology)研究员
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、负责细菌感染疾病或相关免疫系统疾病的药理研究工作;
2、负责药物研发过程中生物靶点识别、靶点验证、疾病机制或生物标记物研究;
3、负责实验数据的分析及解释、报告撰写等,针对项目进展与项目成员或合作者进行有效沟通;
4、项目或部门会议上汇报工作及讨论;
5、指导实验助理进行研究工作;
6、及时了解相关研究领域的最新进展;
7、Work independently in a collaborative team environmentdiscovering novel therapeutics for bacterial infection disease or immunologic disease;
8、Design, perform and optimize assays for target identification, validation, mechanistic study as well as biomarker study;
9、Analyze and interpret experimental data, communicate with team members and collaborators on working progress;
10、Summarize and present research results in the project and department meetings 5、Supervise junior research stuff members (research associate, associate scientist, or research scientist);
11、Keep abreast of the current development in the area of research focus;
12、Act as the scientific resource for the related diseases。
任职要求:
1、微生物学、免疫学或相关专业,0-5年相关研究经历,博士或同等以上学历;
2、具有在工业界小分子化合物药物开发经验者优先考虑;
3、具备药物靶点识别、相关疾病机制研究或生物标记物研究经验者优先考虑;
4、对相关研究领域有深入的了解;
5、具备实验设计、操作、解释及解决问题的能力;
6、对科研工作有热情及兴趣,具有创新意识和学习能力;
7、实验动手能力强,积极主动,责任心强;
8、有良好的团队协作精神和沟通能力;
9、Ph、D or equivalent in microbiology or immunology, with 0- 5 years relevant postdoctoral experience;
10、Industrial experience in small molecule drug development is preferred;
11、Research experience in target identification, disease mechanistic study as well as biomarker study is a desirable;
12、A broad knowledge and deep understanding of disease biology is a must;
13、Demonstrated ability to independently design, execute, interpret, and troubleshoot experiments;
14、Demonstrated ability to balance multiple priorities and timelines;
15、Must be a team player with pro-active behavior,excellent communication, organizational and multi-tasking skills;
16、Highly motivated, innovative researcher capable of critical thinking and ability to work effectively as part of a team in a fast-paced environment。
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生物学助理研究员(Biology)
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、微生物学,分子生物学或者细胞生物学实验,包括生物学实验方法建立,微生物检测,细胞培养或动物实验;
2、负责实验数据记录分析,报告撰写等;
3、项目或部门会议上汇报工作及讨论;
4、Microbiologist, molecular or cell biologists for biologic assay development, microbial detection, cell culture or animal handling, and/or related areas;
5、Maintain accurate documentation of detail experiments and research results;
6、Present research results in project and department meetings。
任职要求:
1、微生物学、分子生物学、细胞生物学、药学或者相关专业,本科以上学历 工作经验不限;
2、有微生物相关工作经验者优先考虑;
3、对科研工作有热情及兴趣;
4、实验动手能力强,积极主动,责任心强。有良好的团队协作精神和沟通能力;
5、B.S. or M.S. degree in microbiology, molecular biology, cell biology, pharmacology, or related areas;
6、With microbiology related working experience is preferable;
7、A strong interest and background in biological research;
8、Ability to work and communicate well within project team;
9、Flexible, able to work on several projects simultaneously。
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药物化学总监,高级总监 (Medicinal Chemistry)
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、负责小分子药物新药研发团队的日常工作包括新型分子的设计,合成方案的制定、化合物的优化,专利的查新与撰写、关键技术难题的解决等小分子药物化学研发过程的管理,参与重要研发节点的监管和决策;
2、追踪国际创新发现及优化的相关平台和技术、及时掌握行业最新动态,为项目提供专业信息支持;
3、负责药物化学部团队的招聘、培训和管理,提升团队研发实力和效率;
4、负责实验室安全责任管理;
5、Respossible for the whole process management of small molecule drug discovery and development including:
Design and execution of small molecule drug candidates;
Planning for chemical synthesis overall schemes;
Patents search and update;
Resolution of key technology puzzles;
Participating major decisions of R&D mile stones;
6、Track worldwide innovative discovery and optimization from relevant platforms、 Keep abreast of the latest development of the industry, provide professional information support for the project;
7、Responsible for the recruitment, training and management of medicinal chemistry team to enhance R&D capacity and efficiency;
8、Responsible for laboratory EHS management。
任职要求:
1、有机化学,药物化学, 计算化学等相关专业、博士学历,具有药物化学10年以上相关经验和不少于5年的药化项目领导经验、有项目成功进入临床阶段者优先,有海外制药公司或生物医药公司工作经验者优先;
2、具备解决新药研发难题的能力,包括化合物合成和优化过程中出现的各种问题,对于化合物成药性有深刻的理解,对于药代动力学和毒理有较深入的了解,能够熟练运用这些知识解决药物发现中的问题;
3、具有良好的组织协调和团队领导能力和经验,具有5年以上10人以上规模团队管理经验;
4、具有团队合作精神、良好的沟通和执行能力,具有很强的主观能动性,高度的责任感和敬业精神;
5、PhD degree in organic chemistry, medicinal chemistry, computational chemistry with more than 10 years of relevant experience in medicinal chemistry and no less than 5 years of experience in drug development projects、 Successful experience with projects into clinical stage is preferred、 Overseas pharmaceutical companies and/or Biopharmaceutical companies working experience is a plus;
6、With strong ability to solve problems related to the hit identification and lead optimization process、 With deep understanding of drugability, pharmacokinetics and toxicology of small molecule drug candidates;
7、Skillful coordination and strong team leadership experience, with more than 5 years of team management experience of more than 10 people;
8、Excellent communication and execution skills, being self-motivated, high sense of responsibility and professionalism。
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分析研究员
999999-999999元/月招聘人数 1人工作地点:上海浦东新区
职位介绍:
1、负责部门内以小分子化合物为主的生物分析方法的开发、验证、优化及执行,负责代谢产物鉴定及体外样品的检测分析工作,参与DMPK/ADMET实验及实验方法的建立,可独立进行实验操作及数据分析;
2、负责查阅研究文献,设计分析平台,完成生物分析方法的开发与验证,充分代表部门的专业能力,为实验提供相关专业意见;
3、熟练阅读各类英文资料,负责实验数据记录分析,报告撰写等;
4、独立分析和解决实验中遇到的异常问题,能够解决简单的仪器故障;
5、Develop and optimize LC-MS/MS bioanalysis and small molecule compound analysis, be responsible for the identification of metabolites and the detection and analysis of in vitro samples, participate in the establishment of DMPK/ADMET experiments and experimental methods, and independently conduct major experiments & data analysis;
6、Be responsible for reviewing research literature, designing assays, completing the development and verification of bioanalytical methods, fully representing the professional capabilities of the department, and providing relevant professional advice for the experiment;
7、Proficiency in reading technical materials including English ones, esponsible for keeping records of the experimental data, report writing etc;
8、Independent analysis and troubleshooting, be responsible for solving simple instrument failures。
任职要求:
1、生物技术、药物分析或生物化学、分析化学等相关专业,本科以上,5年质谱分析相关工作经验者优先考虑;
2、熟练掌握色谱类分析检测原理,熟悉掌握LC-MS/MS仪器,了解Q-Tof和Waters的使用,使用过WinNonlin等类似的处理PKdata的相关软件;
3、熟悉 In vivo PK 生物检测,具有独立分析处理数据经验,熟悉体外ADME、体内PK、生物分析等实验;
4、对科研工作有热情及兴趣,实验动手能力强,积极主动,责任心强;
5、较强的沟通能力,能够独立有效开展工作,能良好的与团队协作;
6、根据该应聘者的实际工作经验及能力、背景等,我们也可能提供/研究员/高级助理研究员等不同职位;
7、Biotechnology, pharmaceutical analysis or biochemistry, analytical chemistry and other related majors, undergraduate and above, 5 years of experience in mass spectrometry related position is preferred;
8、Familiar with chromatographic analysis and detection principles, familiar with LC-MS/MS instruments, user of QTof and Waters, and capable with software such as WinNonlin to process PK data;
9、Eperiences of in vivo PK bioassay analysis and processing, familiar with in vitro ADME, and other experiments;
10、Passionate in scientific research, strong experimental ability, proactive, strong sense of responsibility;
11、Strong communication skills, able to work independently and effectively, and as a teammember。